SUPPORT HOTLINE (888) 901-2226
Donate Now

BRIEF TITLE: Familial and Atypical Urothelial Cancer Registry

Familial and Atypical Urothelial Cancer Registry


  • Org Study ID: 09-025
  • Secondary ID:
  • NCT ID: NCT00902590
  • NCT Alias:
  • Sponsor: Memorial Sloan Kettering Cancer Center - Other
  • Source: Memorial Sloan Kettering Cancer Center

Brief Summary

This study is being done to create a registry to help us learn more about urinary and other cancers. This will let us look at large groups of people who do and do not have this kind of cancer. The investigators will look at risk factors to learn more about how these impact cancer. The investigators will also look at genetic markers. These are genes that are found in a known place. They are often associated with a particular trait. If the gene changes in some way, it may predict cancer or response to treatment. The investigators will look for markers in your saliva. This registry will help us develop better methods of: Preventing these cancers. Diagnosing these cancers. Treating these cancers.

Overal Status Start Date Phase Study Type
Recruiting Start Date: May 2009 Observational

Primary Outcomes:

Primary Outcome 1 - Measure: Determine whether single nucleotide polymorphisms in regions discovered from whole genome scans, such as 8q24 & chromosome 3, & candidate genes, include NAT2 & GSTM1, prev found to be assoc with bladder ca risk, are assoc with UC in this study population

Primary Outcome 1 - Time Frame: 2 years

Condition:

  • Urothelial Cancer
  • Renal Pelvis Cancer
  • Ureter Cancer
  • Bladder Cancer

Eligibility

Criteria:
Inclusion Criteria:

Urothelial Cancer Cases

- Must be ≥ 18 years of age AND

- Must have a diagnosis of urothelial cancer AND

- Must be an English-speaker

Non-Cancer Control Group

- Must be ≥ 18 years of age AND

- Must not have cancer or a personal history of cancer, with the exception of skin
cancer. AND

- Must not be a blood relative of cases AND

- Must not be a blood relative of another control AND

- Must be an English-speaker

Family Member Control Group:

In select kindreds with a high prevalence of bladder cancer and/or very early onset bladder
cancer, first- and second-degree family members of probands may be contacted by the MSKCC
study team and invited to complete the questionnaire and submit a saliva sample.

- Must be ≥ 18 years of age AND

- Must be a blood relative of a case participant AND

- Must be an English-speaker

Exclusion Criteria:

- Have any condition, which in the opinion of the primary MSKCC clinician or
investigators precludes their ability to provide informed consent.
Show More

Gender: All

Minimum Age: 18 Years

Maximum Age: N/A

Healthy Volunteers: Accepts Healthy Volunteers

Official Information

Name: Dean Bajorin, MD

Role: Principal Investigator

Affiliation: Memorial Sloan Kettering Cancer Center

Overall Contact

Name: Dean Bajorin, MD

Phone: 646-422-4333

Email:

Link: Memorial Sloan Kettering Cancer Center

Locations

Facility Status Contact
Memorial Sloan Kettering at Basking Ridge
Basking Ridge, New Jersey 07920
United States
Recruiting Dean Bajorin, MD

Memorial Sloan Kettering Cancer Center @ Suffolk
Commack, New York 11725
United States
Recruiting Dean Bajorin, MD

Memorial Sloan Kettering Cancer Center
New York, New York 10065
United States
Recruiting Dean Bajorin, MD
646-422-4333
Memorial Sloan Kettering Cancer Center at Mercy Medical Center
Rockville Centre, New York 11570
United States
Recruiting Dean Bajorin, MD

Memoral Sloan Kettering Cancer Center@Phelps
Sleepy Hollow, New York
United States
Recruiting Dean Bajorin, MD